AUTOMUTE

AUTO
mated server for predicting...
      ...functional consequences of amino acid MUTations in protEins

tessellated_t4_lysozyme

 

AUTO-MUTE Home

Stability Changes (ΔΔG)

Stability Changes (ΔΔGH2O)


Stability Changes (ΔTm)

Activity Changes

 Disease Potential of Human nsSNPs

Structural Bioinformatics at
George Mason University

Questions or Comments?
mmasso@gmu.edu

Activity Changes


PDB ID
(e.g., 3PHV)

Chain
(use @ if null)

Mutation
(e.g., D25E)

Mutant #1

Mutant #2

Mutant #3

Mutant #4

Mutant #5

Note: Use D25_ to obtain predictions for all 19 substitutions at the requested position.

Classification Model: Random Forest (details)
Prediction: Protein activity is either affected or unaffected as the result of a single amino acid substitution at a particular position.