BINF 731: Protein Structure Analysis

Theoretical topics

Secondary structure prediction (approaches, algorithms)
Structure alignment and comparison
Structure classification (approaches, implementations)
Protein modeling

Structure verification and validation

Machine learning algorithms in protein structure analysis


Practical skills

               Working knowledge of protein sequence and structure databases
               Working knowledge of protein sequence patterns
               Working knowledge of structure visualization tools

 

Databases: UniProt, PDB, Prosite
Tools: Entrez, Biology Workbench, Expasy, Swissmodel