BINF705-001 RESEARCH METHODS - SPRING 2007

Instructor - Jeff Solka, 540-653-1982 (D), (540)-371-3961 (N), 540-809-9799 (Cell), (540)-993-4357 (PW), jlsolka@gmail.com

Office Hours - By Appointment Mondays Ocaquan Rm. 312D

Schedule - Tuesday 6:00 pm - 7:00 pm in OB Room 318

Texts

Francis L. Macrina, Scientific Integrity: Text and Cases in Responsible Conduct of Research (Paperback), 3rd Edition 2005.
Kevin W. Bowyer (Editor), Ethics and Computing (Paperback), 2000.

Course Structure

Each class meeting will consist of a brief lecture followed by class discussions based on reading assignments and professor presented case studies.

Course Description

This course will examine the moral dilemmas that currently face researchers. A particular emphasis will be placed on those issues associated with the use of computers in general and their application in bioinformatics in particular. Some of the topics to be discussed will include the fundamentals of ethics, scientific reporting and ethics, interpersonal relationships within a research setting, ethics and peer review, ethics and whistle blowing, relationships with funding agencies, animal research, human research, fraud, intellectual property, and improper use of computer equipment.

Grading - Grades will be based on a class presentation and class participation.

Breakdown Class Participation (25%), Class Presentation (75%)

Schedule
Week 1 1/23/07
Course Structure, Fundamentals of Ethics, Some Example Ethical Dilemmas
Read Chapter 1 of Macrina.
Read Chapter 1 of Bowyer.

Week 2 1/30/07
TBD
Read Chapter 2 of Macrina
Read Chapter 2 of Bowyer

Week 3 2/6/07
TBD
Read Chapter 3 of Macrina
Read Chapter 3 of Bowyer

Week 4 2/13/07
TBD
Read Chapter 4 of Macrina
Read Chapter 4 of Bowyer

Week 5 2/20/07
Student Presentation Group 1
Brown and Villa-Angulo - Should technologies that radically extend human life spans be allowed to be employed? (Life Extension)
"The Prolongevists Speak Up: ..."

Brown Villa-Angulo Slides

Read Chapter 5 of Macrina
Read Chapter 5 of Bowyer

Week 6 2/27/07
Student Presentation Group 2
Sherril and Von Canon - Should medical care be withheld from those individuals that have made "poor lifestyle choices"? (Managed Care)
Do Smokers Deserve Equal Medical Care?

Sherril Vom Canon Slides

Supplemental Article # 1

Supplemental Article # 2

Supplemental Article # 3

Read Chapter 6 of Macrina
Read Chapter 6 of Bowyer

Week 7 3/6/07
Student Presentation Group 3
Barb and Acharya - Should patient assisted suicide be allowed and if so under what circumstances? (Euthanasia)
The Euthanasia Website

Mekhalla/Barb Slides

Read Chapter 7 of Macrina
Read Chapter 7 of Bowyer

Week 8 3/13/07
No class Spring Break.

Week 9 3/20/07
Student Presentation Group 4
Herrera and Takeda - Should genetic testing be required for jobs or parenthood? (Genetic Testing)
One Points Paper on Genetic Testing in the Workplace

Herrara/Takeda Slides

Read Chapter 8 of Macrina
Read Chapter 8 of Bowyer

Week 10 3/27/07
Student Presentation Group 5
Sharma and Liang - Should individuals be allowed to select the sex of their children or if the technologies should be developed should individuals be allowed to select the traits of their children prior to conception?
The Technology is Here Now!!

Sharma/Liang Slides

Read Chapter 9 of Macrina
Read Chapter 9 of Bowyer

Week 11 4/3/07
Student Presentation Group 6
Kopecky and Kadoi - Does the promise of new drug therapies justify exclusive proprietary access to genetic information? (Intellectual Property)
A Few Pontifications About Intellectual Property Rights.

Kopecky/Kadoi Slides
Read Chapter 10 of Macrina
Read Chapter 10 of Bowyer

Week 12 4/10/07
Student Presentation Group 7
Chang - Animal Testing

Read Chapter 11 of Macrina
Read Chapter 11 of Bowyer

Week 13 4/17/07
Student Presentation Group 8
Walsh and Overal - Do the claims of public safety trump concerns for personal privacy in mandating DNA databanks? (Biometric Analysis)
A Link to the Annual Report of the Canadian DNA Data Bank.
Walsh/Overall Slides

Week 14 4/24/07
Student Presentation Group 9
Tran and Liu - Should patients in chronic pain be allowed whatever pain remediation possible including the use of the strongest opiates such as heroin? (Algology)
A Link to a Political Action Group on Pain Management.
Liu/Tran Slides


Week 15 5/1/07
Student Presentation Group 10
Ryan and Thompson - 24. Should cross species transplantation be allowed? (Xenotransplantation)
One Points Paper on the Ethics of Xenotransplantation.