Course Description:
Surveys computational tools and techniques to study whole genomes and explores biological basis of genome analysis algorithms. Topics include genome maping, comparative genomics, and functional genomics.
Grading Policy:
The course grade will be determined as follows:
90-100 A
Mid-Term Exam - 30%
80-89.9 B
Final Exam - 40%
70-79.9 C
Final Project -
30%
70-79.9 F
Problem sets will be assigned as homework several times during the semester. They will be due two weeks after they are assigned. The assignments will be posted on the course web page. Late homeworks will not be accepted.
Academic Honesty Policy:
Academic dishonesty will not be tolerated. This includes cheating, plagiarism, and falsification of academic records. That being said, you can help each other out on the homework (this does not mean that you can copy each other's homework).
Important Dates :
Monday, January 27 - First Day of Class
Monday, March 10 - No Class - Spring Break
Monday, March 17 - Take-home Mid-Term Exam Posted
Monday, March 24 - Take-home Mid-Term Exam Due
Monday, April 28 and May 5 - Project Reports Due and Project Presentations
Monday, May 5 - Project Presentations and Final Exam Posted - Last Day of Class
Course Schedule
Lecture 1 - Introduction to Genomics -January 27, 2025
Lectuer 2 - Multiscale view of Genomics:Cardiac Calcium Signaling - February 3, 2025
Lectuer 3 - Multiscale view of Genomics:Transcription Factors - February 10, 2025
Lecture 4 - Sequencing and Annotation - February 17, 2025
Lecture 5 - Genomes of Populations - February 24, 2025
Lecture 6 - Genomic Variation - March 3, 2025
Lecture 7 - Clinical Genomics - March 17, 2025
Posted March l7, 2025 - Midterm Take-home Exam
Lecture 8 - Functional Genomics - March 24, 2025
Midterm Exam Due - March 24, 2025
Lecture 9 - Epigenomics - March 31, 2025
Lecture 10 - Agricultural Genomics - April 7, 2025
Lecture 11 - Mitochondrial Genomics - April 14, 2025
Lecture 12 - Pharmacogenomics - April 21, 2025
Final Projects Reports Due - May 5, 2025
Final Project Presentations - April 28, 2025
Final Project Presentations - May 5, 2025
Final Exam Posted - May 5, 2025
Final Exam Due - May 12, 2025
Sage Advice: If you want to do well in course: 1) Do all the problem sets. 2) Read the text book and any other assigned reading. 3) Ask questions in class and office hours. 3) If you are having difficulty doing the problem sets, be sure to get help. I encourage the students discussing the course material and problems, but require everyone to do the work - NO COPYING.