Course Description:
Surveys computational tools and techniques to study whole genomes and explores biological basis of genome analysis algorithms. Topics include genome maping, comparative genomics, and functional genomics.
Grading Policy:
The course grade will be determined as follows:
90-100 A
Mid-Term Exam - 30%
80-89.9 B
Final Exam - 40%
70-79.9 C
Final Project -
30%
70-79.9 F
Problem sets will be assigned as homework several times during the semester. They will be due two weeks after they are assigned. The assignments will be posted on the course web page. Late homeworks will not be accepted.
Academic Honesty Policy:
Academic dishonesty will not be tolerated. This includes cheating, plagiarism, and falsification of academic records. That being said, you can help each other out on the homework (this does not mean that you can copy each other's homework).
Important Dates :
Monday, January 22 - First Day of Class
Monday, March 4 - No Class - Spring Break
Monday, March 11 - Take-home Mid-Term Exam Posted
Monday, March 19 - Take-home Mid-Term Exam Due
Monday, April 22 and 29 - Project Presentations
Monday, April 29 - Project Reports due and Final Exam Posted - Last Day of Class
Course Schedule
Lecture 1 - Introduction to Genomics -January 22, 2024
Lectuer 2 - Multiscale view of Genomics:Cardiac Calcium Signaling - January 29, 2024
Lectuer 3 - Multiscale view of Genomics:Transcription Factors - February 5, 2024
Lecture 4 - Sequencing and Annotation - February 12, 2024
Lecture 5 - Genomes of Populations - February 19, 2024
Lecture 6 - Genomic Variation - February 26, 2024
Posted March ll, 2024 - Midterm Take-home Exam
Lecture 7 - Clinical Genomics - March 18, 2024
Midterm Exam Due - March 18, 2024
Lecture 8 - Functional Genomics - March 25, 2024
Lecture 9 - Epigenomics - April 1, 2024
Lecture 10 - Agricultural Genomics - April 8, 2024
Lecture 11 - Mitochondrial Genomics - April 15, 2024
Lecture 12 - Pharmacogenomics - April 22, 2024
Final Projects Reports Due - April 29, 2024
Final Project Presentations - April 22, 2024
Final Project Presentations - April 28, 2024
Final Exam Posted - April 29, 2024
Final Exam Due - May 6, 2024
Sage Advice: If you want to do well in course: 1) Do all the problem sets. 2) Read the text book and any other assigned reading. 3) Ask questions in class and office hours. 3) If you are having difficulty doing the problem sets, be sure to get help. I encourage the students discussing the course material and problems, but require everyone to do the work - NO COPYING.