YourSeq      : MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDKTLAFKMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHREDSDVEMVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQWALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLPLLIDNYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYSIRKQYISEESTLSGQQSEVPGSIPNSWKWTVEHIVYKALRSHILPPKHFTEDGNILQLANLPDLYKVFERC : YourSeq  
O61917       : EYLQPGVIRKLDEVVVNRIAAGEIIQRPANALKELLENSLDAQSTHIQVQVKAGGLKLLQIQDNGTGIRREDLAIVCERFTTSKLTRFEDLSQIATFGFRGEALASISHVAHLSIQTKTAKEKCGYKATYADGKLQGQPKPCAGNQGTIICIEDLFYNMPQRRQALRSPAEEFQRLSEVLARYAVHNPRVGFTLRKQGDAQPALRTPVASSRSENIRIIYGAAISKELLEFSHRDEVYKFEAECLITQVNYSAKKCQMLLFINQRLVESTALRTSVDSIYATYLPRGHHPFVYMSLTLPPQNLDVNVHPTKHEVHFLYQEEIVDSIKQQVEARLLGSNATRTFYKQLRLPGAP...........DLDETQLADKTQRIYPKEMVRTDSTEQKLDKFLAPLVK...........SD.SGVSS...........................................SSSQEASRLPEES............FRVTAAKKSREVRLSSVLDMRKRVERQCSVQLRSTLKNLVYVGCVDERRALFQHETRLYMCNTRSFSEELFYQRMIYEFQNCSEITICPPLPLKELLILSLESRAAGWTPEDEDKAELADGAADILLKKAPIMREYFGLRISEDGMLESLPSLLHQHRPCVAHLPVYLLRLATEVDWEQETRCFETFCRETARFYAQLDWREGATAVFS..............RWTMEHVLFPAFKKYLLPPR...IKDQIYELTNLPTLYKVFERC : O61917  
O81785       : ....................................................................................................SEQIRDWGWICNITVEGSTS.........FKKN......MSIIQRKPTPITLNAVPCILGVNLSDVD........LLEFLQQLADTDGSSTIPPS....VLRVLNSKACRG.....AIMFGDS....LLP................SECSLIIDG....................LKQTSLCFQCAHGRPTTVPLVDLKALHKQIAKLSGRQVWHGLQRREITLDRAKSRLDNAKS.................................................................................................................................................................................................................................................................................................................................................................................................................................... : O81785  
CAB78038     : TTIVPRKIQRLEESVVNRIAAGEVIQRPVSAVKELVENSLDADSSSISVVVKDGGLKLIQVSDDGHGIRREDLPILCERHTTSKLTKFEDLFSLSSMGFRGEALASMTYVAHVTVTTITKGQIHGYRVSYRDGVMEHEPKACAAVKGTQIMVENLFYNMIARRKTLQNSADDYGKIVDLLSRMAIHYNNVSFSCRKHGAVKADVHSVVSPSRLDSIRSVYGVSVAKNLMKVECDSSGCTFDMEGFISNSNYVAKKTILVLFINDRLVECSALKRAIEIVYAATLPKASKPFVYMSINLPREHVDINIHPTKKEVSLLNQEIIIEMIQSEVEVKLRNANDTRTFQEQKVEYIQSTLTSQ..KSDSPVSQKPSGQKTQKVPVNKMVRTDSSDGRLHAFLQPKPQ...........SLPDKVSS..........................................LSVVRSSVRQRRNP..................KE..TADLSSVQELIAGVDSCCHPGMLETVRNCTYVGMADDVFALVQYNTHLYLANVVNLSKELMYQQTLRRFAHFNAIQLSDPAPLSELILLALKEEDPGNDTKDDLKERIAEMNTELLKEKAEMLEEYFSVHIDSSANLSRLPVILDQYTPDMDRVPEFLLCLGNDVEWEDEKSCFQGVSAAIGNFYAMHPQFYSKRGESSQEKSDLEGNVDMEDEWSIQHVLFPSMRLFLKPPASMASNGTFVKVASLEKLYKIFERC : CAB78038  
Q9XU10       : EFSLMGLIQRLPQDVVNRMAAGEVLARPCNAIKELVENSLDAGATEIMVNMQNGGLKLLQVSDNGKGIEREDFALVCERFATSKLQKFEDLMHMKTYGFRGEALASLSHVAKVNIVSKRADAKCAYQANFLDGKMTADTKPAAGKNGTCITATDLFYNLPTRRNKMTTHGEEAKMVNDTLLRFAIHRPDVSFALR..QNQAGDFRTKGDGNFRDVVCNLLGRDVADTILPLSLNSTRLKFTFTGHISKPIASATAAIFSVFINGRSVRCDILKHPIDEVLG..ARQLHAQFCALHLQIDETRIDVNVHPTKNSVIFLEKEEIIEEIRAYFEKVIGEIFGFEALDVEKMIPMSQSRKPD...KPEFKSSPSAWKSDKKRVDYMEVRTDAKERKIDEFVTRGVGPTTSNGGSGILKRATEDSTGGE.......................................KEPEDLNTDFDDVSMVSLVSTADGRRLNESQDLGEDEFHFESIEVLRKEIIANSSQSLREMFKTSTFVGSIN.KQVLIQFGTSLYHLDFSTVLREFFYQISVFSFGNYGSYRLDEEPP.AIIEILELLGETREPNYAAFEVFANVEAAEKLLAEHADLLHDYFAIKLDQLENITEIPSLVHYFVPQLEKLPFLIATLVN.VDYDDEQNTFRTICRAIGDLFTLDT.FITLDKKISAFSATP........KTLIKEVLMPLVKRKFIPPEHFKQAGVIRQLADSHDLYKVFERC : Q9XU10  
MLH1_YEAST   : ..MSLR.IKALDASVVNKIAAGEIIISPVNALKEMMENSIDANATMIDILVKEGGIKVLQITDNGSGINKADLPILCERFTTSKLQKFEDLSQIQTYGFRGEALASISHVARVTVTTKVKEDRCAWRVSYAEGKMLESPKPVAGKDGTTILVEDLFFNIPSRLRALRSHNDEYSKILDVVGRYAIHSKDIGFSCKKFGDSNYSLSVKPSYTVQDRIRTVFNKSVASNLITFHVED.LNLESVDGKVCNLNFISKKSIPIFFINNRLVTCDLLRRALNSVYSNYLPKGNRPFIYLGIVIDPAAVDVNVHPTKREVRFLSQDEIIEKIANQLHAELSAIDTSRTFKASSLIPFNDTIESDRNRVENSYTTANSQLRKAKRQENKLVRIDASQAKITSFLSSSRQLSEPKSHSQEAEKLTLNESEQPR......................................DANTINDNDLKDQP..K..KKQKLGDYKVPSIADDENVNLTSIKKLREKVDDSIHRELTDIFANLNYVGVVDERLAAIQHDLKLFLIDYGSVCYELFYQIGLTDFANFGKINLQSTNVSDDIVLYNLLSE.FD....ELNDDASKEKIISKIWDMSSMLNEYYSIELVNDGLLKSLPLLLKGYIPSLVKLPFFIYRLGKEVDWEDEQECLDGILREIALLYIPDMKVDTSDASLSEDEKAQ..FINRKESSLLEHVLFPCIKRRFLAPRHILKD..VVEIANLPDLYKVFERC : MLH1_YEAST  
CAB66448     : VNSRAK.IRPLDQLVINKIAAGEIIERPENAIKELIENSLDAGSTSIDVLLKDGGLKLLQITDNGSGIQYDDLPYLCQRFSTSKIDNFNDLQHLQTFGFRGEALASISHVAKVTVVTKLSSDIHAWKAFYVDGGMSPAPQPCAGKQGTVITAEDLFYNVRSRKSALKNGSEEFRRIMILVQKYAIHNDQVSFNCKKVGDTVASLSLSSRLSKADKIRHIYGPRVASHLRDFSGQSSIVGFSANGFISNADFQDKKSNLILFINNRLVESVELRHALEETYAKYLHKGASYFVYLSLNMSPEQLDVNVHPSKRIVHFLYDQEIATSICDKLGEILERTDTER....SY..PLQAMIPS....ISNTKNAESSSQKAVRTYENYLVRTDPRERSIKSMLSDNLQRS...SNNYDNEIIEKVDSAN.........................................SNKNATNDIKD..............LQTEEIVEE.SIDLESIKSLQKQVINSMHVLATNILTEHKYVGLVCPRIAAVQHNIGLYVVDYGKLSYHLFYQICLTEFGNYGEFVLETP.....LSISDLFEI.VN....GDEDKSESEKFTRLLVSRRDMLKDYFSISVTSGGLLTAVPMLSPKYHPPFEQLPLLISSLTKFFDWLDEKSCLNGIMKAIAKFYVP........LPLSYEESD....VKSIRESCLEDYLFPEFRRRVICPKKVFEEKCIYQITSLPRLYNVFERC : CAB66448  
PMS1_SCHPO   : ...MST.VKPIDANTVHKICSGQVITDVASAVKELVENSLDSGATTIEIRFKNYGINSIEVVDNGSGIDAGDYESIGKKHFTSKITDFEDLEALQTFGFRGEALSSLCAVGQVIISTATQEAPKGVQLNLDHE.SLKDKLTIPFQRGTSVMVNDLFCTLPVRRKLLENYKREFSKAISLLQAYATISTNKRFMVYKNSGKLLQLSTNSNKDMKLNIMNVFGTKVSSSLIPWN.DGIIEGYISRPHVGSTRASNER..QMLFINRRLVNLPKIAR.VIQEVFKPYSMAQSPFFAINLRITNGTIDINVSPDKKSVFLSEEDSIIEFIKNSLQNLCESCGHAISCSRSQIFSYSSQSTDQELPTESETSDDSSFSYKRSPCKRKLVEATAQPASLAQVSKPLSSPLNEKSERMKKKLASTDTSMQKTIDS..........................SFPLKQPINKPSSNPNNLLLNDPSPASTPVAKTINLNEIESVHNARIPSKTAALQKLKFFQSRPLDGLNKFSKKINISLVQKSDALLKFSNKIGVVHDISQEDHLNLTVHKADFLRMRVVGQFNRG....FIVVVHGNNIIDQHASDEKFNYEHLKSNLVINSQDLVLPKRLDLAATEETVRKGFGVAIDLNQRVGNRCTLLSVPTS..KNVIFDTSDLLEIISVLSEHPQIDPFSSRLERMLASKACRSSVMIGRAL.ISEMNTIVRHLAELSKPWNCPHGRPTMRHLLRLKDI....... : PMS1_SCHPO  
Q9TVL8       : .MSQNK.IERISKEVAERLTTAQVVVSLSSAIRQLIDNSIDAGSTIIDIRVKNNGFESIEVQDNGSGIEARNFDALCKPHSTSKLTQFSDFDKLATLGFRGEALNALCTVSSVSIFTRASDTEIGTRLTYDHSGNIICRQSAARELGTTIIVNKLFETLPVRRKELESQKREFVKLLSTVQSFALLCPHIKILCTNGKKTNLICTPGGTTSIQDVVANLFGIAIGSGLIPIQEMHFFDLFKIRGFVSSCEHGCGRGTQFVYINNRPVEYSRVCS.VINDVYKQFNKKQYPIIVLFIDVPPEKIDVNVTPDKKTVMLEKERHLLAVVRASMMKTYLKIVGSHSTVRSSIMNLSQQMSSKSSTLNSTYPEDSLLNTSDLLKQRKENRSPPAKRRTEPFHSVPTSNSRTQFSFTMEPKRKKIPSKSDK...............................KLTDEELRSAVIEENPLKKAGEIDDIEILEQSQESQDVNESQCTLRPQQKIKFSMKLLREAYSPKTDETDDNTEEAEVS.KDVLNEITTKINKEENDDAERQLSRSLTKDDFSKMKIIGQFNHG....FIICRLRGHIVDQHASDEKYNFERLQSSAKLTKQPLFMPTALGFGAVQELIANGFDFEFSENDGCIKTFLTARPELL...NQQLTNSDLEEILAVVSQYPNQMY.PVRIRKIFASKACRKSVMIGKPL.QREMTQIIRHLAKLDQPWNCPHGRPTIRHLASLPDRAEFE... : Q9TVL8  
PMS2_MOUSE   : .TECAKAIKPIDGKSVHQICSGQVILSLSTAVKELIENSVDAGATTIDLRLKDYGVDLIEVSDNGCGVEEENFEGLALKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHGSASVGTRLVFDHNGKITQKTPYPRPKGTTVSVQHLFYTLPVRYKEFQNIKKEYSKMVQVLQAYCIISAGVRVSCTGQGKRHAVVCTSGTSGMKENIGSVFGQKQLQSLIP..TSGRHKTFSTFRASFHSARTAPGGVQTGSFSSSIRGPVTQQRSLSMRFYHMYNRHQYPFVVLNVSVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDANKLNVNQQPEKPVPGKKSTADEKREAFSLHPTKEIKSRGPETAELTRSFPSESDVISYRGLRVSPTDSPDREKIEKDSTSAGSEEEFSTPEVASSFSSDYNVSSRPSQETINCGDLDCRPPGTGQSLKPEDHGYQCKALPLARLSPTNAKRFKTEERPSNVEVDVAIKMNKRIVLLEFSLSSLAKRMKQLQHLKAQN.ELSYRKFRAKICPGENQAAEDELRKEISKSMFAEMEILGQFNLG....FIVTKLKEDLVDQHAADEKYNFEMLQQHTVLQAQRLITPQTLNLTAVNEAVKNGFDFVIDEDAPVTERAKLISLPTS..KNWTFGPQDIDELIFMLSDSP.GVM.PSRVRQMFASRACRKSVMIGTAL.ASEMKKLITHMGEMDHPWNCPHGRPTMRHVANLDVISQN.... : PMS2_MOUSE  
Q9V7B6       : TTALSGQIKAIGKDTVHKICSGQVVLSLAVAVKELVENSIDAGATLVEIKLKDQGLQSVEVSDNGSGVEEMNLEGMTAKYHTSKIREFVDLLGVETFGFRGEALSSLCALSDMVIQTRHKSTDVGVKVELDHEGRIKKRSPCARGVGTTVLLANLFSTLPVRRRDFTNIKKEFTKMCQILQAYCLVTKGVRILCSPKGAKTIVLQTHGDQEVMANISAIFGARQAADLVPLKGADLADTTSPQISTEDVERLNQADFLEGFISSCRHGAGRSSRDVMNEVYHRYNVQQQPFIYLNIITARSDVDVNLTPDKRQLLINNERILLLALKKSLLDTFGQTPATFQMQNTTKFPKESSVSEEDVPDVLTQWRRTGDTKGTAPSVPVKRRCSESEQKIHTFLSQESSKCEAESDVDMAKKDTQVSLDNSFLNLKELAKESEAYDLLTTPRIDCKVLTPIKSRRSIFEFKTDAMALDKQESPAELNSQPPSFTQLSEETDIASDEEMEEGLPSNFSSGEITTSLEEIASSLKAHEQQQRDRRKLQRLRFKTEINPNQNTSAEAELQREIDKEDFARMEIIGQFNLG....FIIVKLEDDIVDQHATDEKYNFETLQRTTQLEYQRLAVPQNLELTAVNEMVKNGFKFEVDHEAPATKKVRLLGKPHS..KRWEFGKEDIDELIFMLQDAPEGTI.PSRVRAMFASRACRKSVMIGTAL.NTTMRRLITQMGEIEQPWNCPHGRPTMRHLINIAMLINSDEND : Q9V7B6  
Q9RP66       : ..........................................................LQISSRAKGAK................................DAFSILVEGGQVGEVAPAA.....................FPGPHGARIEVRDLFYATPARLKFMKSERAEALAITEEIKRQAMANESVGFSLDGRRVLRLPPEHPGPQGRLARLAAVLGREFQENALEID..QTRDGVRLSGFAGLPTYNRGNAAQYLFVNGRPVRDRLLQGALRAAYADFLARDRHPTAALYVTLETTEVDVNVHPAKAEVRFRDPALVRGLIVGALRHALAGAGHRASTTVAA.................QALDSIRAQQSPFPGYQPQYQPGPSPAGFSAWREGG................WTPPTQRP.....................................MDLPGLNEVSARVEPS.............YGGDLAG..VVREAYAAAAFEDRPPTDYPGATAPFDPVDYPLGARATYIVAQTRDGMVIVDQHAAHERLVYERMKGEMASGGVTRQTLLLP....EVVDLDPA................EAERVVARAEELAGLGLVLESFGPG..AVLVRETPALLGKTDAAALVRDIAD.DLAENGQALALKERLEEVCSTMACHG.SVRAGRRLNG...............AEMNALLREMEATPHSGQCNHGRP.TYVELKLADIEKLFGRR : Q9RP66  
MUTL_BACSU   : ...MAK.VIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSKIKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTG.EGAGTKLVLQGG.NIISESRSSSRKGTEIVVSNLFFNTPARLKYMKTVHTELGNITDVVNRIALAHPEVSIRLR..HHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLH.VS.SLDFEVKGYIALPEITRASRNMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDGIKDVFKQQQLIPSAQVPK...KSAP.........AIKNEQQFITFDEKPPEKKVPEKSTAPMKLSSVVKEP................VDAEEKLP........................................PLQFDAPPIVDQ..............EQTLEVS..DVSAEQPETFEQECHEEQPQPASDRVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVGEVEPEVQEMIVP....LTFHYSTN..................EALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQ..QVLDSKNIDIKKLREEAAIMMSCKG.SIKANRHLRND...............EIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM : MUTL_BACSU  
MUTL_TREPA   : FSMHETPIHRLSPDTAKKIAAGEVIERPASVVRELLENALDAGATKIHLEINAGGCALIRVSDNGHGMSPQDLLLCAEAHTTSKISSADDLLQLRTLGFRGEALASIAAVSRLHLTSTRSAGTAAHVPPVPQGTEAGVLEPASLERGTVVRVEQLFENFPARKRFLGRQSAETTLCRSALIDVSLAHHPVEFRFTDGTHKLTLLSQQTRKDRCLETQMLKGDP..ALFHTIE.GG.DCSFHFHLVLSEPAICRRERRIFTFVNGRRIFDYGLVQALVLGSEGYFPNGTFPVACLFLTVNSERIDFNIHPAKKEVHLQDYAHIRHTLSRSVAHFYRQCTIAHYVRAEP...AHAP.........ATQGNAPTHSSPPCTGVREEPAAPCAHPRYESLFPLP................VQHAHLLP.......................................PSPPHISCEHAR..........................DCTHPAPAAEGDAPVHNHTHTGAFKVLGQVAG...TFIAVERNNALYLIDQHAAHERIIFDTLQRNLGTAQILLIPYH.......IHPRSDE................EARIMHRACTELSPAGFRFHEEPDGS.WHVTAVPLHWRGSEEQLAHDILYSG.....KNAHDILRHVLATCACRSACKD.TILDDATLHS.....................LVEQAFALPQSRCPHGRP.IWIVIGRDELFKRIKRT : MUTL_TREPA  
consv        : -------1--1--------1-2-11-----112---21-131-11-1-1-----2---1-1-1-2-2----1-------1-2231----3-----1-2121857226516627-316113----2----------------331-167-816218524514634-62----2---622182246321--226142----21-141--41-3-----31746-1----522----------------2-3114112-------1------------8-213---312-2245445-816112-466641648125151212-81--32212---412--------------------------------------------------------------------------------------------1----------1-----------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-----------1------------------------------------ : consv

             : 1---------11--------21--------31--------41--------51--------61--------71--------81--------91--------101-------111-------121-------131-------141-------151-------161-------171-------181-------191-------201-------211-------221-------231-------241-------251-------261-------271-------281-------291-------301-------311-------321-------331-------341-------351-------361-------371-------381-------391-------401-------411-------421-------431-------441-------451-------461-------471-------481-------491-------501-------511-------521-------531-------541-------551-------561-------571-------581-------591-------601-------611-------621-------631-------641-------651-------661-------671-------681-------691-------701-------711-------721-------731-------741-------751--- :
OrigSeq      : MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDKTLAFKMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHREDSDVEMVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQWALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLPLLIDNYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYSIRKQYISEESTLSGQQSEVPGSIPNSWKWTVEHIVYKALRSHILPPKHFTEDGNILQLANLPDLYKVFERC : OrigSeq

jalign       : ------HEH-----HHHHHH---EEE--HHHHHHHHH--------EEEEEEH----EEEEEE----------HHHHHHHH----HHHH--HHHHHHH---HHHHHHHHH-EEEEEEEEE------EEEEE------------------EEEEEE-HH-HHHHHHH-----HHHHHHHHHHHHHHHH----EEEE-----EEEEEE---------EEEEEE-------------------E-----------------EEEEE----------HHHHHHHHHHHH------EEEEEEE-----EEEE-----HHHHHH-HHHHHHHHHHHHHHHHH-----------------------------------------------------------EE--------------------------------------------------------------------------------------------------------HHHHHHHHHHH-----------------HHHH-HHHHHHHHHH---EEEE---HHHHHHHHHHHHHHH----HEE-------HHEEEEE-------------HHHHHHHHHHHHHHHHHHHHHH--HHEH----------EE----------HHHHHH-----------HHHHHHHHHHHHH----------H-HHH-------------HHHHHHHHHHHHHHH--------------EEEEE--HHHHHH---- : jalign
jfreq        : ----HHHHH-----HHEEEH--EEEE-HHHHHHHHHHHHHH---HHHHHHHHH---EEEEEE--------H-HHHHHHH-----------HHHHHH----HHHHHHHHHH-EEEEEEEE------EEEEE-----------------EEEEEEHHH----HHHHHH----HHHHHHHHHHHHHHHH---EEEEEE----EEEEEE------HHHHHHHHH-HHHHHHHHEEE------EEEEEEE-----------EEEEEE------HHHHHHHHHHHHHHH-------EEEEEE----------------EEEE----HHHHHHHHHHHHHH------HHHHHH------------------------------------------------------------------------------------EE------------------------------------------------EE--------HE-------EEEEHHHHHHHHHH-----HHHHEEEE--EEEE---HHHHHHHH---EEEE----HHHHHHHHHHHHHHH---EEE------HHHHHHHHH------------HHHHHHHHHHHHHHHHHHH---HEEEEE-------------------------EHEH----------H--HHHHHHHHHHHHH----EE---------------------H-HHHHHHHHHHHH-------------EEEEE-----EEEEE-- : jfreq
jhmm         : ------------HHHHHHH-HHHHEE-HHHHHHHHHHHH------EHHHHHHH---EEEEEE------HHHHHHHHHHH----------HHHHHHH-----HHHHHHHHH--EEEEEEE----EEEEEEE------------------EEEEE---HHHHHHHHH----HHHHHHHHHHHHHHHH-----EEEE-----EEEEE-------HHHHHHHHH-HHHHHHH-----------EEEEEEEE---------EEEEEE------------HHHHHHHHHH-----EEEEEEEE-----EEEEEE---EEEE---HHHHHHHHHHHHHHHH-------EEEE--E----------------------------------------------E--------------------------------HHHHH----------------------------------------------------------------------HHHHHHHHHH-----------------------HHEEEHHH---E--E--HHHHHHHHHHHHHHHH----EE---------EEEEEE----------------HHHHHHHHHHHHHHHHHH----EEEE---------EE-----------EEE--------E----HHHHHHHHHHHHH----------------------------HHHHHHHHHHHHHHHHH------------EEEEE----HHH----- : jhmm
jnet         : ----HHHH----HHHHHHHHH--EE--HHHHHHHHHHHHH-----EEEEEE-----EEEEEE-------HHHHHHHHHH----------HHHHHHHH---HHHHHHHHHH--EEEEEEE-----EEEEEE------------------EEEEE-HHHHHHHHHHHH---HHHHHHHHHHHHHHHHH----EEEEEE---EEEEEE------HHHHHHHHHHHHHHHH--EEEE------EEEEEEE----------EEEEEE-------HHHHHHHHHHHHHH-------EEEEEEE-----EEEE------EEEE---HHHHHHHHHHHHHHH------HHHHHHH-------------------------------------------------------------------------------------------------------------------------------------E---------EEE------EEEHHHHHHHHHHHH----HHHHHHH---EEEE---HHHHHHHH---EEEEE-HHHHHHHHHHHHHHHH----EEE------HHHHHHHHH------------HHHHHHHHHHHHHHHHHHHH---EEEEEE------------------------EEE-----------HHHHHHHHHHHHHHHH-----E--------------------HHHHHHHHHHHHHHHH------------EEEEE----HHHHH--- : jnet
jpssm        : ------------HHHHHHHH--HHHH--HHHHHHHHH--H-----EEEEEEE---EEEEEEE-------HHHHHHHH--------------HHHHHH-----HHHHHHH---EEEEEEE-----EEEEEEE-----EEEE--------EEEEEHHHHHHHHHHHHH---HHHHHHHHHHHHHHH------EEEEEE---EEEEEE------HHHHHHHHH-HHHHHH---EEE------EEEEEEE----------EEEEEE-------HHHHHHHHHHHHHH------EEEEEEEE-----EEEEE-----EEEE----HHHHHHHHHHHHHH------HHHHHHH---------------------------------------------------------------------------------HHHH-------------------------E---------------------------------EE------EEEHHHHHHHHHHHHH-HHHHHHHHHH--EEEEEE-HHHHHHH---EEEEEEEHHHHHHHHHHHHHHHH----EEE------HHHHHHHH--------------HHHHHHHHHHHHHH--HHHHHEEEEEEE---HHHHHHHHH----------HEEEEH----------H-HHHHHHHHHHHHHH--------------------------HHHHHHHHHHHHHHHH------------EEEEE---HHHHH---- : jpssm
mul          : ---HHH-HHHH-HH-HHHHHHHHEEEE--HHHHHHHHH-------EEEEEE-----EEEEE-----------HHHHHH---------HHHHHHH-------HHHHHHHHH-EEEEEE--------EEEE-------------------EEEEEHHHHH-----HHHH----HHHHHHHHHHHHHH-----EEEE------EEEEE-----------EEEE--HHHHHHH----------------------------EEEEE------HHHHHHHHHHHHHHH-------EEEEEEE------EEEE-----HHHHHHHHHHHHHHHHHHHHHHHH-------------------------------------------------------HHH-----------------------------------------------------------------------------------------------------------HH--HHHHHHHHHHH----HHHHHH-----------HHHHH----EEEE-----HHHHHHHHHHHHH-----------------EEHHH--H-----------HHHHHHHHHHHHHHHHHHHH-HHHH----------EEEH--------HHHHHHHH-----------HHHHHHHHHHHHH-----------HHHHHH-------------HHHHHHHHHHHHH-------------EEEE---H-HHHHHHH- : mul
phd          : --------HHH-HHHHHHHH---EE-HHHHHHHHHHHHHHH----EEEEEEE----EEEEEE-----------HHHHHH--------HHHHHHHHHH---HHHHHHHH--EEEEEEEE--------EEEE------------------EEEEE-------HHHHHHH--HHHHHHHHHHHHHHHHH---EEEEE-------EE-------HHHHHHHHHH--HHHH--------------EE---------------EEEEEE--------HHHHHHHHHHHHH------EEEEEEE------EE-------EEEE---HHHHHHHHHHHHHHHHH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHHHHHH---------HHH------E-------EEEEE---EEE----HHHHHHHHHHHHHHH-----EEE---------EEEE----------------HHHHHHHHHHHHHHHHHH---EEEEE-----------------------EEEE-------------HHHHHHHHHHHHH-----------------------------HHHHHHHHHHHHHH------------EEEEE---HHHHHH--- : phd
pred         : --------HHHHHHHHHHHH---EEE---HHHHHHHHHH------EEEEEEE---EEEEEE------EEE---------------HHHHHHHHH------HHHHHHHHHHEEEEEEE------EEEEEE------------------EEEEEE--HHHHHHHHHHHH---HHHHHHHHHHHHHHH------EEEE-----EEEEE----------EEEEE-HHHHHHHHH------EEEEE---------------EEEEEE----HHHHHHHHHHHHHHHHH-------EEEEEEE--------------EEEEEHHHHHHHHHHHHHHHHHHH-----EEE---------------------------------------------HHHHHHHHHH--------------------------HHHHHHHHHH---------------------------------------------HHHHH-HHHHHHH-------EEEHHHHHHHHHHHHHH-HHHHHHHHHHH-------HHHHHHHHHHHHEEE--HHHHHHHHHHHHHHHH----EEEE-----HHHHHHHHHH-----------HHHHHHHHHHHHHHHHHHHHHHHHEEEE----------EEE---------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--EEEE-----------------HHHHHHHHHHHHHHHHHH-----------EEEEE------EEEE--- : pred
zpred        : ---------------HHH--H-EEEE-HHHHHHHHHHHHHHHHHHHEEEEE-----EEEEE----------HHHHHHHH--------HHHHHH-------HHHHHHHHHHEEEEEEEE--------EEE-----------------EEEEEEEEEEEEHHHHHHHH---HHHHHHHHHHHHHHEEE----EEEE-----EEEEEE------EEEEEEEEEE-----EEEE--------------------------EEEEE-----------HHHHEEEEH-------EEEEEEEEEEEHHHEEEEE--HHHHHHHHHHHHHHHHHHHHHHHHHH----------------------------------------------EE----------EEE-------------------------------------------------------------------------------------------------------HHHHHHHHHHHHHH--------HHHH-----------HHHHHH-----EE-----HHHHHHHHHH--------------------EEEHH---------------HHHHHHHHHHHHHHHHHHHHHHHHHHH--------EEEE-------HHHHHHHH--------HHHHHHHHHHHHHHH---------------------------------HHHHHHHHHH---------------EEEE---HHHHHH---- : zpred

Jpred        : ------------HHHHHHHH---EEE-HHHHHHHHHHHHH-----EEEEEE-----EEEEEE----------HHHHHHH----------HHHHHHHH---HHHHHHHHHH--EEEEEEE-----EEEEEE------------------EEEEE--HHHHHHHHHHH---HHHHHHHHHHHHHHHHH----EEEEE----EEEEEE------HHHHHHHHH-HHHHHH------------EEEEEE-----------EEEEEE-------HHHHHHHHHHHHHH-------EEEEEEE-----EEEE------EEEE---HHHHHHHHHHHHHHH-------HHHH----------------------------------------------------------------------------------------------------------------------------------------------------------EEEHHHHHHHHHHH-----HHHHHH----EEEE---HHHHHHHH---EEEE--HHHHHHHHHHHHHHHH----EEE------HHHHHHHH-------------HHHHHHHHHHHHHHHHHHHHH---EEEEE------------------------EEE-----------HHHHHHHHHHHHHHHH--------------------------HHHHHHHHHHHHHHHH------------EEEEE----HHHH---- : Jpred


PHDHtm       : ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ : PHDHtm
MCoil        :  : MCoil
MCoilDI      :  : MCoilDI
MCoilTRI     :  : MCoilTRI
Lupas 21     : ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ : Lupas 21
Lupas 14     : ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ : Lupas 14
Lupas 28     : ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ : Lupas 28

PHDacc       : --BBB-BB--B---BB--BBBB-BBB-BB-BB--BB--BB-B-B-BB-BBB---BB-BB-BB-----B----B-BBB--UB---BU-B--BB-BBBB-B-B-BBBBBBBBB-BBBBB-U----BBB-BBB-----U-----BB---BBBBBBBBBBBBB-BUU--B--U---BB-BB-BBBBBBBB---B-BBB------BBBB-------BB-BBBBBBBU-BB--BB-B-B--BBBBB-B-BBBBBB-BBB--BBBBBBBBBUBB-BBBBU-BBBBBBBBBBB---UBBBBBBB-B---UB-BBBU-----BBBB---BBB-BB--BB--BB--B-BBUBB-BB-BB-B---U----B---B-------------------B--------B-BBB--------------B------B--------B--BB-BB-BB-BBB---B-BBBBB-B-B-B----B---------U---B-B-BB--B----B----------B-B-BB--B---BB--BB--B---B--BBBBBBB---BBBB-B-B-BBBB-BB-BB--BB--BB---BB-B-BBBBBU-U-BB-BBBBBB---BB---B------B-B--BB-BBB--B-BB--BBBB-BB--BBB-BBBBBB--BB--B--BBBBBBUBB--B-U-----BB--BB-BBB-BBBB---BB-B-B-BB---B---BBBBUBB-BBBBBBBB-BB--BB----BU--U-BBBBBB-B--BB-BB--- : PHDacc
Jnet_25      : --BB---B--B---BB--BBBB-BB--BB-BB-BBB-BBB-B-BB-BBB-B---BB-BBBBBB-B-BB---BB--BB--BBBB-B--B-BB--B-BBBBBB-BBBBBBBBB-BBBBB------BBBBB-B-----------B-----BBBBB-BBBBBBBBBB--B-----BB--BB-BB--BBBB---B-BBB---------BB------B--BBB-BBB--BB--BB-B-B------B-B-BBBBBB-BBB--BBBBBBBBBB-B-B--B--BB--BBB-BB----BBBBBBBB-B---BBBBBBBB----BBB-----BB-BBB--B---B--------B--B----------------------------------------------B-BB-------B--------------------------BB-B---B-----------------B----------------B-----B----------B-B--------B-B--B--B---B---BB--BB-BB--B-BBBBBB--BBBBBB-B-BBBB-B--BB-BBBBBBBB-BBB-B--B-B---BBB-BBBBBBB------B---------BB--BB-BB--B--BB--BBBBBB---BBB-BBBBBB--BBB-B--BBBBBBBBB--B-B-----BB--BB-BBB-BB-B---BB-----B----------B---B-BBBB-BBB-BB---B-B---B----BBB-BB-B--BB-BB--B : Jnet_25
Jnet_5       : -------B------B---B----B-------B--BB--B-------B-B-B-------B-B-----------B--BB----------------B--B-B-B-BB-BBB-BB-B-B---------B--B-B-----------------B-B-B--BB---------B---------B---B---B-----B-B-B---------------------B--------------B----------B-B-B-----------BBBBBB--------B---B-------------BBBBBBB-B----B-B-B------B-B-----B---B---B--------------------------------------------------------------------------------------------------------------------------------------------------------------------------B-------B-----------B---B-------------B-B-----BB-B----B---B--------B----------------BB-B----------------------B---B----------B-B-B--------B--BB---------B--B----------------B--B---B---------------------------------------B---B---------------B--B-----B--B---- : Jnet_5
Jnet_0       : -------------------------------------------------------------------------------------------------------------------------------------------------------B-----------------------B---------------------------------------B-------------------------------------------B-B----------------------------BB-B---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------B---B---------------------------------------B---B-------------------------------- : Jnet_0

PHD Rel      : 987545430101257643212522201379999999984435874468997248953788934888875443046564222332211224457764133257877531122589985245776642442037767898878888998336752111234212444301136778999999997641367156761587631221457652125677755422333301234666543321112212334333456505999715423433123466777754321367724899984477751431268961332124227999999999997642244221213445778899997878888877788778888888766544589865442331358898989888787677888767788889965422467764556577776477888887777788987777777788899877777787665655555667522333202344321223554211211223420123431112332240232146246789999987752113311444258987520455314666665455543321456778999987774321441554226664444332135687654422012245654454455315899999998742147875432333345568766644664204767788899876347897789998415652331265323269 : PHD Rel
Pred Rel     : 006666858077888777766656606766888098966677766569096069059800989999778668856665556666855866888758888687788784586668665687766655885676666699899988908687965655856888888857666788899988877767798806586779877776678898867687766866788885756878886565566667766666666856776578666558888889999888788809860096667689987666799905597778889999999999887706999055566756788889899766679887889999999676756565687776788888058887679999877678978788997768668788368776858675677899797765555787889889778677777777777776888758689777666688888899998776665898888666066668778877897788667056658887999997868668666777709966658809888899999899976888099999999999999998765696608966667666858989980066768088558788788788888889988878556765566976667756898988677888878880888858608909866776678966797686866000 : Predator Rel
Jnet Rel     : 444340102558479977771333428489999999440301873111321138866999981888780676999837338744562120511221122527378777418469998324898148999807873045652789998368750034422777997127505899999999984272898189996117728897628997569999999626998732415513578738787665178778999768998647876836899999999998637899619999865188622220167740688546167999999999887415884358877512455567875565667888877788888764666556689875675312146788889988756876788876556677651111158998889998887778766554131468999999888899988751025899875412115885254042688999986141625677765244277403316999642882988924145589899999876236541470688654899888707988999988782899999999999956503304406898347441112301647886432362111113787767673378999999999886236740145876653232456776532569767899999876116898644688179970775346541279 : Jnet Rel

Note on coiled coil predictions - = < 50% probability c = >50% <90% probability C = >90% probability