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                                             BIOINFORMATICS COLLOQUIUM
						College of Science
                                              George Mason University
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            Genomic approaches to defining mechanisms of transcriptional regulation in mammalian cells 
						 
                                               Kevin Gardner


Abstract:
The availability of whole genome sequences for a wide variety of organism has completely changed the 
way we think of and investigate biology. As we approach the post-genomic era it is now clear that 
the biological complexity of all living things is not defined by the genomic size or gene number.  
Rather, it is the manner in which the genes are regulated. Determining the molecular events and logic 
that controls the follow of genome-based information during cellular processes has fast become the new 
challenge of the 21st century. In this seminar I will discuss approaches and strategies to leverage 
genomic information through cell-based assays to begin to define decipher and define mechanisms of 
transcriptional control.