----------------------------------------------------------------------- BIOINFORMATICS COLLOQUIUM College of Science George Mason University ----------------------------------------------------------------------- Determining Differentially Expressed Genes: Is Using Statistics From Each Probe of an Affymetrix Array a Good Approach? Alan Berger Naval Surface Warfare Center - Dahlgren Biography: Alan E. Berger is an applied mathematician at the Naval Surface Warfare Center - Dahlgren. He earned his B.A. degree in Mathematics from Rutgers University in 1968, and Ph.D. in Mathematics from MIT in 1972. He has done research in the areas of numerical analysis of elliptic equations, free boundary problems, and singular perturbation problems. He has done interdisciplinary collaborative research in deriving computable expressions for the intensities of sidebands in solid state NMR spectra with magic angle spinning thereby permitting determination of the principal values of chemical shift tensors from experimental data, in modeling the reversible assembly of amphiphilic molecules into aggregates that can form liquid crystalline phases with preferential orientation distributions, and in modeling equations of state of certain polymers. Recent interests include the protein folding problem, which led to his current involvement in analyzing gene microarray data. Dr. Berger can be contacted at alan.berger@navy.mil